- Treatment of acromegaly in patients who have had an inadequate response to surgery, and/or radiation therapy, and/or other medical therapies or for whom these therapies are not appropriate
|Drug||Dosing Regimen||Dose Limit/ Maximum Dose|
Sandostatin LAR depotR (octreotide)*
10 to 40 mg IM q 4 weeks
40 mg q 4 weeks
Somatuline depotR (lanreotide)
60 to 120 mg SC q 4 weeks
120 mg q 4 weeks
100 - 500 mcg SC TID
|Drug||Dosing Regimen||Authorization Limit|
40 mg loading dose SC followed by 10 mg SC QD adjusted to serum IGF-I levels.
Maximum daily maintenance dose:
6 months with re-approval upon demonstrated age-adjusted IGF-I levels in the normal range.