- The treatment of HIV patients with wasting or cachexia to increase lean body mass and body weight, and to improve physical endurance. Concomitant antiretroviral therapy is necessary.
All of the following must be met:
Drug | Dosing Regimen | Dose Limit/ Maximum Dose |
---|---|---|
Appetite stimulants |
|
|
Appetite stimulants | 2.5 mg PO bid | 20 mg/day |
Testosterone replacement products |
|
|
Testosterone replacement products | 2.5 - 7.5 mg/day patch applied topically QD | 7.5 gm/day |
Testosterone replacement products | 5 - 10 gm gel (delivers 5 - 10 mg testosterone) applied topically QD | 10 gm/day gel (10 mg/day testosterone) |
Testosterone replacement products | 5 - 10 gm gel (delivers 5 - 10 mg testosterone) applied topically QD | 10 gm/day gel (10 mg/day testosterone) |
Anabolic steroids |
|
|
Anabolic steroids | 100 mg IM Q 1-2wks | 100 mg Q wk |
Drug | Dosing Regimen | Authorization Limit |
---|---|---|
Serostim | < 35 kg = 0.1 mg/kg SC daily 35 to 45 kg = 4 mg SC daily 45 kg to 55 kg = 5 mg SC daily > 55 kg = 6 mg SC daily | Initial authorization: 12 wks Reauthorization: Up to 6 months based on positive response to therapy which is defined as 2% increase in body weight and/or BCM. Note: Once BCM is normalized, therapy may be stopped and the patient may be monitored for wasting to reoccur. |