- Routine prophylaxis against angioedema attacks in adolescent and adult patients with Hereditary Angioedema (HAE).
|Drug||Dosing Regimen||Dose Limit/ Maximum Dose|
Long-term prophylaxis in adults:
200 mg two or three times PO daily initially.
Maintenance doses determined by decreasing this dose by 50% or
less at intervals of 1 to 3 months or longer while edematous attacks are prevented.
If an attack occurs, the dose can be increased by up to 200 mg.
Short-term prophylaxis in adults:
|Drug||Dosing Regimen||Authorization Limit|
500-1500 units IV one time up to
24 hours prior to the procedure
1,000 units IV every 3 or 4 days
Short term prophylaxis:
Vial: 500 units