- Acute, intermittent treatment of hypomobility, "off" episodes ("end-of-dose wearing off" and unpredictable "on/off" episodes) associated with advanced Parkinsons disease.
|Drug||Dosing Regimen||Dose Limit/ Maximum Dose|
200 mg PO with each dose of carbidopa/levodopa
0.5-1 mg PO QD
5 mg PO BID
25 mg/100 mg PO BID; 50 mg/200 mg PO BID
10 mg/100 mg PO 3 to 4 times daily; 25 mg/100 mg PO 3 times daily
carbidopa 200 mg/day
0.25 mg PO TID titrate weekly to 3-9 mg PO TID
0.375 mg PO daily in three divided doses increase every 5 to 7 days as needed.
1.5 - 4.5 mg/ day
StalevoR (carbidopa, levodopa and entacapone)
Conversion of treatment regimen already stabilized on equivalent doses of carbidopa-levodopa and Comtan:
Conversion from tx without Comtan:
1600 mg/day (of entacapone)
|Drug||Dosing Regimen||Authorization Limit|
0.2 ml SC initial test dose.
Length of benefit